Hi Eric,
Cilofexor is the name that Gilead gave their experimental drug GS-9674. I have been involved in the study here in the Detroit area since 11/29/19.
Originally, I had a fair amount of itching when I first started taking the medication, which is a common side affect (go figure) but my body seems to have adjusted as I haven’t had that problem for a while.
The way it was explained to me, the drug is supposed to work by inhibiting bile production, thereby reducing damage to the liver over time. I did notice a slight drop in bilirubin when I first started taking it, but, due to coronavirus and shelter in place mandates in Michigan, I haven’t had any blood work drawn for several months now.
I think this is going to more of a see where you are in two years approach, regarding MRCP, liver biopsy, and lab results, before we’ll know for sure if it is really helping.
I started a thread regarding my experience so far, which I have linked below. I haven’t updated it lately, just because there hasn’t been anything to say
Best of luck. I hope you are able to get started in the study soon. Please feel free to reach out if you have any questions.
Steve