I can’t loose wait and have tried everything short of just eating all greens. Eat minimal meat take supplements over last 6 months due to a rigorous physical fitness management position. Run, exercise several hrs a day 4-5 days a week. Meld ranges from 14-17 currently lower at 13-14. 10 yr diagnosed 41 yr old male. I try to eat fruits nuts low fat or as low fat as reasonable. Sugar here and there is my biggest downfall. But even when I have curbed sugar to a low, I can’t seem to loose more than a pound or two. Any thoughts ideas, I’m worried about trying a glp1.
My hepatologist gave me her blessing to try glp-1 a year and a half ago. I’m a 56 year old female and my PSC has been pretty stable since I was diagnosed 9 years ago. I’ve successfully lost 95 lbs and it has changed my life for the better. I would recommend asking your hepatologist first, since it can cause pancreatitis and lately I’ve heard bile duct cancer? I also want to add that I have had 2 flares this year with fever and elevated enzymes. It could be related to the tirzepetide, but no one seems to know enough about glp-1s in my area to say for sure.
I have more energy, my body hurts less (fibromyalgia almost completely gone), and I feel so much better and happier in general. That being said, I am also cautious about losing too much weight just because if my PSC takes a turn I’ve seen how almost skeletal many people get before a transplant comes and that weighs on being in good health for the transplant surgery. Hope this helps at least a little and good luck!
1 Like
Marlena, welcome back!
Marlena,
Such wonderful news to hear you are doing so well. I know you feel much better with the weight loss. Regarding PSC and weight loss, you certainly don’t want to go overboard on losing too much weight, but keep in mind that if one is really overweight, that will have a bearing on your recovery and how you handle the surgery. It’s a delicate balance for sure. For me, I think the biggest reason for the weight loss was just the loss of appetite towards the end. You feel miserable; just the smell of food made me nauseated at times, or even going with my wife to the grocery store. In fact we had to get an electric skillet for her to cook some foods like hamburgers out on the back porch as the smell really bothered me. Yet I could go to McDonald’s and eat a hamburger and fries and do just fine. We are all so different in how this disease manifests itself.
Continue to live your life to the fullest each day. I sincerely wish you the very best and hope you will have improved health for many years to come.
Mark
PSC 2011 / Liver Transplant 2015