Calling All Transplant Success Stories

We would like to invite all those who have had successful liver transplant experiences to please share your story with the group. A new transplant discussion category has been recently started called "Let's Talk About Transplants" and we would like to hear your story of success. There are those awaiting transplants who would love to hear all the details that you feel comfortable sharing about your experience as we anxiously await that all important life-changing phone call. So please step right up and share your success story with all of us.

Mark

Hi I am Mary,

June 23rd of this year I will be 11 years post liver transplant. For many years I had uc and then I developed psc.

Although hard, I continued to work and found out that being active was the best thing I could have done. That doesn't mean that I wasn't fatigued and even fell asleep at my desk once. Your doctor, however will be your best advisor on this matter. There were many tests before I was placed on the transplant list. Because of my B blood I thought I would not be likely to get a transplant but the social worker told me it could bring me right up. That is just what happened because in two weeks I got the call. I am wishing the same thing for all who are waiting for the call. I know waiting is hard but someday you will be surprised. I was sitting at me desk when the call came. I think in 11 years things probably have improved tremendously. It is a hard surgery and you will need patience. But the day will come when you will forget you even have a new liver and enjoy a tremendous increase in health and well being. It is very important to do all the doctors tell you and to keep taking the medications they give you and remember to eat healthy foods. I am rooting for all of you and in your corner. Please ask me anything you are wondering about as I am here to help you.

Mary

It is 3 years and 4 months since my living donor liver transplant at Northwestern Memorial Hospital in Chicago. My hepatologist calls my liver a "superstar," because of the blood test results I get each month. My PSC diagnosis goes back to 2000. I have had UC my whole life. Most of the time it is in remission. When they diagnosed PSC, the doctor told me PSC had caused the UC.

I had End-stage IV liver cirrhosis in 2007 and began having liver failure episodes starting in 2009. I was on two cadaver transplant lists, one in Milwaukee and the other at Univ. of Wisconsin in Madison. After waiting on the lists for an organ for 3.5 years, the transplant surgeon at UW told me PSC does not score accurately on the Model for End-stage Liver Disease, which is what they use to allocate cadaver livers. He said my liver was in very bad shape, that I would not live long enough to qualify for a cadaver and that I needed to find a living donor.

My family is small and only two relatives were the same blood type, the first qualification before being evaluated at greater length. My daughter was tested, but did not match anatomically. My nephew lived in the Middle East with three little children and was disqualified. My daughter posted my story on Facebook. A childhood girlfriend contacted her and volunteered to be tested. She was a perfect match.

The surgeries took place two weeks later. They were done by two different surgical teams. They opened me first to make sure there were no hidden complications such as cancer. They coordinate the removal of my entire liver with removing 2/3rds of my donor's liver. A live donor transplant takes longer than a cadaver transplant, generally speaking. This is because they have to hook up a mid-point on the donor liver with the core where my old liver was attached.

As soon as I regained consciousness, I wanted to know how my donor was. Her husband wheeled her into my room. Seeing her smile and holding her hand assured me she was going to be fine. Her recovery took about a month. Within two months, her liver had grown back to normal size. The piece I received grew back in 6 months. My full recovery took 12 months.

My surgeon said a liver transplant is the most complicated surgery there is. I failed to mention that I went to Chicago's Northwestern Memorial Hospital for the living donor transplant because they had the most experience doing them.

Unlike many PSCer's, I absolutely needed a transplant to live. I was one who could not be managed the rest of my life. Some are, but I was not. My new liver functions perfectly. I take 1mg of Prograf 2 times a day for rejection and a prescription antacid called Pantoprazole just once a day. That's all the post surgery medicine I have to take. I can't begin to tell you how grateful I am.

Is a post-transplant thread going to be opened up? I think it would be good to have transplant stories in one spot so PSCer's facing that situation or just wanting to know more about it could draw on our experiences. Believe me, there is a lot more detail about the transplant experience than what I have generalized about in this post. I would be very happy to answer questions about it or share more on the transplant topic. Gosh! There is soooo much someone learns ramping up to the transplant, such as medical tests to qualify for the list and your own fitness for such a challenging surgery.

I do not want to scare anybody away from the surgery. You get through it. You just take one step at a time. I had great transplant team care, and they are just as available and caring today as they were back then. If it is right for your, don't hesitate.

Where might one find out more about the medical tests to qualify and level of fitness to prepare for surgery. Also, how do you know when you are past the point of just managing your PSC? Was your PSC progressing in a manner that you knew a transplant was the direction you were headed at some point?

I spoke with a local woman today who had PSC and she had her transplant 20 years ago! Encouraging news.

My husband was diagnosed with PSC in February of 2007. He was listed on November 3 of 2010 and received a liver on May 3 of 2011 at Barnes Jewish Hospital. He was called in as a backup in February of 2011, which was devastating fot us but amazing for the primary person! His transplant went very well. He did have a leak that was repaired two days after transplant. He was up and walking the very next day! He was active but somehow got pneumonia which kept him in the hospital for an extra four days. He spent a total of 14 days in the hospital. Once he was home he would have me drop him off at a store every morning and he would walk for an hour. Sometimes he would bring one of our kids and sometimes he would go alone. He wanted to build his strength as fast as possible. I believe in my heart this helped him so much, pushing himself! While he does have PCS again, came back within two years, we continue to be thankful for the four years we have had. He continues to fight, like so many of you do, and he belives in his doctors and their care. He has been able to celebrate birthdays, graduations, has pulled a few teeth and been a part of our lives because of a successful transplant.

I'm 2 yrs. with my new liver. I'm 68 yrs. old and became very ill (MELD score over 40) before my transplant. That may explain some of my complications, which kept me in the hospital for a total of 106 days over three admissions, including three weeks at the top of the list. Rather than dwell on the nature of the complications I would like to resurrect a posting that I made months ago about what I wished I knew before I had the transplant. See attached. I am now enjoying life and feel very fortunate to have a liver that is keeping me alive!

Stay Strong!

EAD3

10-AtLastTheLiverTransplant.docx (149 KB)

This message is for Paul Hain,

I was so surprised that your doctor told you that it was the psc that caused the uc. I thought it was just the opposite.

Do you have any more information on this? I am very interested. I think this will be of interest to others.

Thank you from,

Mary

UC is associated with 10% of PSC patients. The exact causes of both diseases are unknown, however auto-immune conditions are suspected in both. They can develop independently or together. I thought, as you did, that I first had UC and then developed PSC. I thought this because the GI that first treated my UC said my liver enzymes were "a little" high. Something, he said, that occurred sometimes after a long, serious bought with UC.

After I was diagnosed with PSC, I asked my hepatologist if UC had caused my PSC. He said that the reverse was most likely: PSC caused the UC. That's all I have to go on.

Paul: Your statistics is way off…
UC is associated with about 75% of psc patients.
About 5% of uc patients will have psc.

Neither is the cause for the other. They have likely common cause that makes it more likely to have these.

A quick comment to Sarah A... my situation was similar, PSC came back 2 years post transplant - but its in remmission now and I plan to keep it that way. If your on this site, I'm sure you've seen the threads on Vancomycin. I have read that its not for everybody - but to be sure it may be for more than we think (for example i am non-IBD but it still works, surprising even the Vanco experts). Its also prohibiitively expensive for some and that is a crime. However, I got a script via my GP (he has more guts than my GI's), have been using it for 8 months now and LFT's rapidly went to normal and are steady eddy normal. Even my transplant team doesn't have a clue about this treatment, and are not really sure what to do with me now that I've cured myself. I would suggest you read up on this treatment and consider going down the road to trying to get it prescribed if you can.

RJM

Thank you so much for this information. I forwarded it onto my husband. I am so happy for your success.

rjm said:

A quick comment to Sarah A... my situation was similar, PSC came back 2 years post transplant - but its in remmission now and I plan to keep it that way. If your on this site, I'm sure you've seen the threads on Vancomycin. I have read that its not for everybody - but to be sure it may be for more than we think (for example i am non-IBD but it still works, surprising even the Vanco experts). Its also prohibiitively expensive for some and that is a crime. However, I got a script via my GP (he has more guts than my GI's), have been using it for 8 months now and LFT's rapidly went to normal and are steady eddy normal. Even my transplant team doesn't have a clue about this treatment, and are not really sure what to do with me now that I've cured myself. I would suggest you read up on this treatment and consider going down the road to trying to get it prescribed if you can.

RJM