May I ask what Vancomycin brand is your daughter using? And what stage of the PSC was she at before starting Vanco?
It took my 20yrs old daughter (stage 2 PSC with UC, 14yrs old at the time of the diagnosis) 4 1/2 years on Vancomycin (IV liquid formulation) for her MRCP to show no beading and for the colonoscopy to be normal. Her LFTs normalized since 2015/2016. In her case the Fibroscan showed a 19.5kPa score in 2015 and she is now down to 6kPa.
To get an idea of the progress you will have to look at the combination between LFTs, MRCP, Colonoscopy and Fibroscan results.
Hope that helps,
Daniela