I believe the theory was - since it is an antibiotic - that you needed to spread out the dosing evenly through the day to maintain a constant level. BUT on carefully listening (and relistening) to this posting by Cactusgirl, Hypothesis on Vancomycin 'brand' differences for PSC effectiveness - #15 by Cactusgirl , I notice the Doctors there talk about a simpler twice a day dosing of Vancomycin for PSC. I think I’m interpreting it correctly that this is how they are prescribing for some patients. I’ve actually been kind of curious about this myself because switching to 2 times a day (2 * 250 mg for me) would de-complicate life a bit. And so I’ve been doing so without confirmation on the basis of the Doc’s discussion in that video. Anyone out there, correct me if they think otherwise - maybe Cactusgirl can weigh in on if the 2 times a day vanco dosing is actually in practice.
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