# Covid Vaccine and PSC Flareups

**URL:** <https://forum.livingwithpsc.org/t/covid-vaccine-and-psc-flareups/4614>\
**Category:** What's New With You?\
**Created:** [May 18, 2021, 4:21pm UTC](https://forum.livingwithpsc.org/t/covid-vaccine-and-psc-flareups/4614 "2021-05-18T16:21:49Z")\
**Posts on this page:** 7\
**Page:** 1

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**Author:** ![DaveCJ](https://sea1.discourse-cdn.com/flex019/user_avatar/forum.livingwithpsc.org/davecj/32/415_2.png) [@DaveCJ](https://forum.livingwithpsc.org/u/DaveCJ)\
**Post date:** [May 18, 2021, 4:21pm UTC](https://forum.livingwithpsc.org/t/covid-vaccine-and-psc-flareups/4614/1 "2021-05-18T16:21:49Z")

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I was diagnosed with PSC about 11 years ago. Fortunately it seems to be slowly progressing. I just received my second Covid shot two weeks ago. A few days ago I had my first PSC flareup in over a year. Has anyone experienced any correlation between the Covid vaccines and PSC flareups?..Dave

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**Author:** ![pendragon](https://sea1.discourse-cdn.com/flex019/user_avatar/forum.livingwithpsc.org/pendragon/32/784_2.png) [@pendragon](https://forum.livingwithpsc.org/u/pendragon)\
**Post date:** [May 19, 2021, 9:30pm UTC](https://forum.livingwithpsc.org/t/covid-vaccine-and-psc-flareups/4614/2 "2021-05-19T21:30:12Z")

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Hi, in a similar situation and had both Astra Zenaca jabs with zero side effects whatsoever.

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**Author:** ![wtm](https://avatars.discourse-cdn.com/v4/letter/w/85f322/32.png) [@wtm](https://forum.livingwithpsc.org/u/wtm)\
**Post date:** [May 21, 2021, 1:20pm UTC](https://forum.livingwithpsc.org/t/covid-vaccine-and-psc-flareups/4614/3 "2021-05-21T13:20:21Z")

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My PSC has remained mild for 14 years with periodic flareups. Had both Moderna vaccines with no issues.

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**Author:** ![MzzP](https://sea1.discourse-cdn.com/flex019/user_avatar/forum.livingwithpsc.org/mzzp/32/1962_2.png) [@MzzP](https://forum.livingwithpsc.org/u/MzzP)\
**Post date:** [May 21, 2021, 4:55pm UTC](https://forum.livingwithpsc.org/t/covid-vaccine-and-psc-flareups/4614/4 "2021-05-21T16:55:01Z")

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I’m sorry to read this- I had Pfizer 2 shots, no issues  
Another buddy post transplant had Moderna 2 shots, no issues

What is a PSC Flare Up to you?  
I hear flare up more in response to UC, Chrons, IBD/IBS

Hang in there 💪🏿😊

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**Author:** ![DaveCJ](https://sea1.discourse-cdn.com/flex019/user_avatar/forum.livingwithpsc.org/davecj/32/415_2.png) [@DaveCJ](https://forum.livingwithpsc.org/u/DaveCJ)\
**Post date:** [May 21, 2021, 5:41pm UTC](https://forum.livingwithpsc.org/t/covid-vaccine-and-psc-flareups/4614/5 "2021-05-21T17:41:02Z")

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Hello MzzP, thank you for your response…and for the good news about no correlation between the shots and flareups…I also had the 2 shot Moderna…To answer your question, a flareup to me is pain starting in the upper right stomach area, a general sense of fatigue and body aches…accompanied with fever and chills…When I feel this coming on I start with my stash of Cipro, 500mg twice a day…generally if I can keep the fever below 102 I avoid a hospital stay…so that’s the goal…usually after 5 days of Cipro, I’m back to “normal”…lol…take care…Dave

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**Author:** ![DaveCJ](https://sea1.discourse-cdn.com/flex019/user_avatar/forum.livingwithpsc.org/davecj/32/415_2.png) [@DaveCJ](https://forum.livingwithpsc.org/u/DaveCJ)\
**Post date:** [May 21, 2021, 5:42pm UTC](https://forum.livingwithpsc.org/t/covid-vaccine-and-psc-flareups/4614/6 "2021-05-21T17:42:21Z")

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thank you…good to hear…Dave

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**Author:** ![DaveCJ](https://sea1.discourse-cdn.com/flex019/user_avatar/forum.livingwithpsc.org/davecj/32/415_2.png) [@DaveCJ](https://forum.livingwithpsc.org/u/DaveCJ)\
**Post date:** [May 21, 2021, 5:43pm UTC](https://forum.livingwithpsc.org/t/covid-vaccine-and-psc-flareups/4614/7 "2021-05-21T17:43:05Z")

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thank you…nice to know…Dave